Ip 10 chemokine

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August undefined, 2024

Web靶标信息. IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. WebIP-10 is a member of the chemokine family of cytokines and is induced in a variety of cells in response to interferon 3' and lipopolysaccharide. The self-aggregation common to …

Interferon gamma-induced protein 10 (IP-10) and cardiovascular

Web7 nov. 2024 · IP-10 was originally identified as an IFN-gamma-inducible gene in monocytes, fibroblasts and endothelial cells. The mouse homolog of human IP-10, CRG-2, shares … WebThis study explores the protective effects of β-FNA when treatment occurs 10 h after LPS administration and is the first-ever investigation of the sex-dependent effects of β-FNA on LPS-induced inflammation in the brain and peripheral tissues, including the intestines. incommunities annual report

Bruton tyrosine kinase inhibitors for multiple sclerosis Nature ...

Web11 jun. 2024 · C-X-C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10 kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the … Web27 mei 2002 · The structure of IP-10 was solved by NMR spectroscopy and represents the first structure from the class of agonists toward the receptor CXCR3. CXCR3 binding chemokines are unique in their ability to bind receptors from both the CC and CXC classes of chemokine receptors ... Macromolecules Find similar proteins by: (by identity cutoff) … WebIP-10 induction by E75 required HLA-A2 presentation and B7-CD28 interactions and was partially inhibited by blocking of CD40-CD40L interactions. These results indicate … incommon rsa

Recombinant Human IP-10 (CXCL10) - PeproTech

IFN-γ-Inducible Protein 10 (IP-10; CXCL10)-Deficient Mice Reveal a …

WebCXCL9, CXCL10, and CXCL11 (also known as Mig, IP-10, and I-TAC, respectively) form a structurally and functionally related subgroup of non-ELR CXC chemokines that … WebChemokine (C-X-C motif) ligand 10 (CXCL10) is a small cytokine belonging to the CXC chemokine family. CXCL10 is secreted by several cell types. These cell types include … incommons mexiaWebIP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated … incommons federation

"Web7 apr. 2024 · IRAK-M knockdown increased the lung epithelial production of cytokines and chemokines, including IL-6, IL-8, CXCL10, and CXCL11, at both mRNA and ... The T cell-specific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells. J Immunol. 1999;162:3549–58. Article CAS PubMed ... " - Ip 10 chemokine

Ip 10 chemokine

CXCL10 - an overview ScienceDirect Topics

Web2 apr. 2024 · While IFN is not readily measurable in plasma, interferon gamma-inducible protein 10 (IP-10, also known as C-X-C motif chemokine 10 or CXCL10) may serve as a … WebDescription IP-10 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of 8.6kDa. The IP-10 is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Formulation

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WebAbstract IP-10, a member of the CXC family of chemokines, is considered to play an important role in inflammation via its T-cell chemotactic and adhesion-promoting … Web(3) Interferon-gamma-induced protein 10 (IP-10) IP-10 is another chemokine with effects similar to those of IL-8. Unlike MGSA, IP-10 is inducible by interferon-7 or TNF-a (Boorsma etal, 1993). IP-10 is also expressed in vivo after application of contact sensitizer or irritants (Kaplan et al, 1987) and may contribute to skin inflam-

Web1 jun. 2004 · Human interferon-inducible protein 10 (IP-10; HGMW-approved gene symbol CXCL10) is an ELR − CXC chemokine that contains binding domains for both the chemokine receptor CXCR3 and glycosaminoglycans. IP-10 has been recently demonstrated to be a potent angiostatic protein in vivo. Web1 mrt. 2024 · Interferon-γ (IFN-γ)-induced protein 10 (IP-10 or CXCL-10) is a chemokine involved in trafficking immune cells to inflammatory sites. Numerous studies have …

Web21 mrt. 2024 · Eine Arbeit konnte die Schwere der Oxigenierungsstörung und die Entwicklung eines ARDS klar mit einem Anstieg der Zytokine, C-X-C motif chemokine 10 (CXCL10) = Interferon gamma- induzierendes Protein 10 (IP-10), Chemokine (C-C motif) ligand 7 (CCL7) = monocyte-chemotactic protein 3 ( MCP3) und dem Interleukin-1 … WebIP-10 is considered a member of the CXC chemokine subfamily from its protein sequence which includes the four conserved cysteine residues present in CXC …

WebSuppression of IP-10 synthesis during the healing phase may allow formation of the wound neovessels, a critical process for infarct healing. Chemokine expression is also noted after a single brief ischemic insult in the absence of myocardial infarction, suggesting a potential role for a chemokine-induced inflammatory response in noninfarctive ischemic …

Web29 okt. 2024 · The serum IP-10, MCP-1 and MIP1α level in both groups was detected using the enzyme-linked immunosorbent assay (ELISA) kit. The clinical symptoms, laboratory … incommunities accountsWebMany studies have shown that production of a chemotactic gradient through the secretion of CXCL chemokines by intestinal epithelial cells may be one the mechanisms attracting leukocytes in particular neutrophils into the epithelial cell layer. 18,19 Several ELR + CXC chemokines are implicated in IBD; for example, CXCL1-2, CXCL5-7, and CXCL8 … inches on a scaleWeb1 jul. 2008 · Interferon--inducible protein (IP-10; CXCL10; 10 kDa) belongs to the CXC family of chemokines and is secreted by a variety of cell types (Baggiolini et al. , 1997). incommons wacoWebNeutrophil-derived chemokine levels are increased in pathological conditions and participate in the inflammatory response by recruiting immune cells to the site of inflammation; they are important mediators of inflammatory and immune responses, underlying the induction of interferon (IFN)-γ and IFN-γ dependent CXC chemokines [7], … incommunities allocation policyWeb它是一种促凝和血管抑制因子，称为血小板因子4，现在更名为CXCL4。从1984年到1989年，一些研究人员克隆了许多结构相关的cDNA，包括IP-10、JE、Mig、RANTES、I-309、KC和MIP-1α等。当时，还没有把趋化功能归因于这个不断增长的基因家族，直到白细胞介素8（IL-8），也称为CXCL8的中性粒细胞趋化特性发现后，趋化因子诱导细胞趋化的功能 … inches on a fingerWebIP-10 (Interferon-gamma inducible Protein 10kDa) also known as CXCL10, is secreted by several cell types in response to IFNg and LPS. These cell types include monocytes, … incommons mexia txWeb1 jul. 1995 · Furthermore, IP-10 shares with PF4 the ability to inhibit endothelial cell proliferation (IC50 = 150 nM). These studies demonstrate specificity in the interaction of … incommonwith.com