WebIntratubular precipitation of these crystals can lead to acute renal insufficiency. Many patients who require treatment with these medications have additional risk factors, such … Webdevelopment of renal failure. Several different drugs have been described to induce crystal nephropathy, including acyclovir and the protease inhibitor indinavir. Renal injury associated with antiviral drugs involves diverse processes having effects on the renal transporters, as well as on tubule cells. In this article, we review the

Drug-Induced Nephrotoxicity AAFP

WebDrug-Induced Kidney Stones and Crystalline Nephropathy: Pathophysiology, Prevention and Treatment. Drug-induced calculi represent 1-2% of all renal calculi. The … WebNov 15, 2011 · Acute interstitial nephritis, crystal nephropathy: Aminoglycosides: Tubular cell toxicity: Amphotericin B: Tubular cell toxicity: Chinese herbal preparations containing … northampton sharps collection

Crystal-induced acute kidney injury - UpToDate

WebValacyclovir 20 mg/kg/dose (max 1000 mg/dose) enterally bid For patients unable to tolerate enteral therapy: Acyclovir 5 mg/kg/dose IV q8h Enteral therapy is preferred if … WebMar 9, 2010 · Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy. It is characterized by a decrease in renal … Webinduced nephropathy. The patient refused to undergo re-nal biopsy and was initiated on aggressive IV fluids. The patient’s renal function began to improve toward baseline over the following week. Discussion Valacyclovir is a widely used antiviral agent in herpetic in-fections and is approved as two single-dose therapy (2 g how to repair yard inflatables