WebAug 16, 2013 · Introduction: Benzofuran moiety constitutes the core of several interesting pharmacologically active natural products. Benzofurans are among feasible potent active inhibitors against many diseases, viruses, microbes, fungus and enzymes. Several series of therapeutically important synthetic and naturally occurring benzofuran-containing … WebDec 29, 2024 · Bioactive Benzofuran Derivatives: A Review. Article. Nov 2014; Hena Khanam; Shams Uzzaman; In nature's collection of biologically active heterocycles, benzofuran derivatives constitute a major ...
Benzofuran derivatives and their anti-tubercular, anti-bacterial ...
WebMar 10, 2024 · By screening bioactive molecules similar to “SalC” with SwissSimilarity, a series of benzofuran derivatives were found in the ChEMB database . These compounds were then exported to SwissADME and docked with JAK (PDB: 6DBN), and the compounds with drug-like properties and JAK affinity potential are recorded in Figure 7 and Table 4 . WebSep 19, 2024 · The study presents the influence of structure modulation by introducing selected donor and acceptor substituents on optical properties of benzofuran used in biological imaging. As the starting form, 2-(5-formylbenzofuran-2-yl)acetamide described experimentally was used. This molecule contains an aldehyde group as reactive site, … dave grohl play album
Bioactive benzofuran derivatives: An insight on lead …
WebAMP-activated protein kinase (AMPK) has been proposed as a therapeutic target for the treatment of metabolic syndrome including obesity and type-2 diabetes. The bioassay-guided fractionation of an EtOAc-soluble extract of the stem bark of Erythrina abyssinica led to the isolation of a new coumestan, erythribyssin N (1), and two new benzofurans, … WebAlso, this study systematically provides a comprehensive report on current developments in benzofuran-based compounds as antioxidant agents and is also helpful for the researchers working on a substitution pattern around the nucleus, with an aim to help medicinal chemists to develop structure activity relationships (SAR) on these derivatives as ... WebJul 12, 2024 · Additionally, we found a novel, simple, and reasonable method to achieve previously reported amide–aniline-bearing phthalides (1-(arylamino)-3-oxo-1,3-dihydroisobenzofuran-1-carboxamides) from diaminoisocoumarin (3-amino-4-(4-arylamino)-1 H-isochromen-1-ones) moieties, based on an oxidative ring contracting … black and grey lehenga